Controlled superficial assembly of DNA–amorphous calcium phosphate nanocomposite spheres for surface-mediated gene delivery

Ayako Oyanea^a, Hiroko Araki^a, Maki Nakamura^a, Yoshiki Shimizu^a, Quazi T.H. Shubhra^a, Atsuo Ito^b, Hideo Tsurushima^{a, c}

^a Nanomaterials Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan
^b Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
^c Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan

SAMCO table-top RIE systsm was used for surface modification of polystyrene substrates in an oxygen plasma.